{"product_id":"p-5-p-bioactive-vitamin-b6-klaire-labs-b003pqn8m8","title":"Klaire Labs SFI Health P-5-P – Bioactive Vitamin B6 (Pyridoxal-5-Phosphate) – 30 mg, 250 Vegetarian Capsules","description":"\u003ch2\u003eWhy Choose Klaire Labs P-5-P?\u003c\/h2\u003e\u003cp\u003eNot all vitamin B6 supplements are created equal. Klaire Labs has earned the trust of health care professionals with its commitment to hypoallergenic, practitioner-tested formulations. This product is designed for individuals with sensitivities or those following strict dietary protocols.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypoallergenic Formula:\u003c\/strong\u003e Free from milk, casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, and yeast. No artificial colours, flavours, or preservatives.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegetarian Capsules:\u003c\/strong\u003e Made from plant-based materials, suitable for vegans and vegetarians.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePractitioner Trust:\u003c\/strong\u003e Developed with input from clinicians and used by practitioners for decades.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient Dosage:\u003c\/strong\u003e Each capsule provides 30 mg – a therapeutic amount for targeted support. The 250-capsule bottle offers a long-lasting supply.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhat Is Pyridoxal-5-Phosphate (P-5-P)?\u003c\/h2\u003e\u003cp\u003eVitamin B6 occurs in several forms, but pyridoxal-5-phosphate (P-5-P) is the most biologically active. It serves as a coenzyme for over 100 enzymes involved in amino acid, carbohydrate, and lipid metabolism. Unlike the more common supplement form, pyridoxine HCl, P-5-P does not require conversion in the liver. This makes it particularly valuable for individuals with liver conditions, genetic polymorphisms (such as MTHFR), or those seeking maximum bioavailability.*\u003c\/p\u003e\u003cp\u003eKlaire Labs SFI Health P-5-P delivers 30 mg of this active coenzyme per capsule in a hypoallergenic vegetarian formula. Trusted by health care professionals since 1969, Klaire Labs emphasises purity and potency, ensuring each batch meets rigorous quality standards.\u003c\/p\u003e\u003ch2\u003eHow Is P-5-P Different from Regular Vitamin B6?\u003c\/h2\u003e\u003cp\u003eStandard vitamin B6 supplements usually contain pyridoxine HCl (PN), which must be converted to P-5-P by the liver. This conversion involves two enzymatic steps and can be inefficient in some people due to genetic variations (e.g., in the enzyme pyridoxal kinase) or liver impairment. In contrast, P-5-P is the final active form, bypassing these conversion steps. Research suggests that P-5-P may be better absorbed and retained in the body, making it a preferred choice for those seeking enhanced bioavailability.*\u003c\/p\u003e\u003ch2\u003eHealth Benefits of Bioactive Vitamin B6\u003c\/h2\u003e\u003cp\u003eThe body relies on P-5-P for a wide range of physiological processes. Here are some of the key areas where this coenzyme makes a difference:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy Production:\u003c\/strong\u003e Vitamin B6 contributes to normal energy-yielding metabolism, helping to sustain energy levels throughout the day.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Health:\u003c\/strong\u003e It works with folate and vitamin B12 to support normal homocysteine metabolism, thereby maintaining healthy homocysteine levels.* Elevated homocysteine is a known risk factor for cardiovascular issues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurotransmitter Synthesis:\u003c\/strong\u003e This coenzyme contributes to normal psychological function and is required for the synthesis of serotonin, dopamine, norepinephrine, and GABA.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Function:\u003c\/strong\u003e Vitamin B6 contributes to the normal function of the immune system, supporting a healthy immune response.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormonal Balance:\u003c\/strong\u003e By aiding in the metabolism of steroid hormones, P-5-P may help maintain hormonal equilibrium, particularly during the menstrual cycle.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduction of Tiredness and Fatigue:\u003c\/strong\u003e Vitamin B6 contributes to the reduction of tiredness and fatigue, making it valuable for overall vitality.*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eThese multifaceted roles make vitamin B6 a foundational nutrient for overall wellness. Choosing the active form ensures that your body can utilise it efficiently.*\u003c\/p\u003e\u003ch2\u003eWho Can Benefit from P-5-P?\u003c\/h2\u003e\u003cp\u003eWhile everyone needs vitamin B6, certain groups may particularly benefit from the active P-5-P form:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eIndividuals with liver conditions or compromised liver function.\u003c\/li\u003e\n\u003cli\u003eThose with MTHFR or other genetic polymorphisms affecting methylation.\u003c\/li\u003e\n\u003cli\u003ePeople on medications that deplete B6, such as oral contraceptives or certain anticonvulsants.*\u003c\/li\u003e\n\u003cli\u003eAthletes and active individuals who require efficient energy metabolism.\u003c\/li\u003e\n\u003cli\u003eOlder adults, as nutrient absorption and conversion may decline with age.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAs always, consult a health care professional before starting any new supplement regimen.\u003c\/p\u003e\u003ch2\u003eSafety and Precautions\u003c\/h2\u003e\u003cp\u003eVitamin B6 is generally well-tolerated. The tolerable upper intake level (UL) for adults is 100 mg per day. This product provides 30 mg per capsule, which is below the UL. However, long-term use of very high doses (over 200 mg daily) has been associated with peripheral neuropathy. If you experience any tingling or numbness, discontinue use and consult your doctor. This product is a food supplement and should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Keep out of reach of children.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eThese statements have not been evaluated by the Medicines and Health care products Regulatory Agency (MHRA). This product is not intended to diagnose, treat, , or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SFI Health","offers":[{"title":"Default Title","offer_id":46715439448225,"sku":null,"price":69.89,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0740\/0043\/3313\/files\/61p0zAzWFGL._AC_SL1500_4256db9f-9df0-4123-a3f8-5291d0d7d263.jpg?v=1784393063","url":"https:\/\/ukvitalityvitamins.co.uk\/products\/p-5-p-bioactive-vitamin-b6-klaire-labs-b003pqn8m8","provider":"UkVitalityVitamins","version":"1.0","type":"link"}