Designs for Health P-5-P - 50mg Vitamin B6 (Pyridoxal-5-Phosphate), 120 Capsules

Why Choose Designs for Health P-5-P?

Practitioners across the UK trust Designs for Health for its commitment to evidence-based formulations. Their P-5-P supplement delivers 50 mg of pyridoxal-5-phosphate, the bioactive form of vitamin B6, in a single daily capsule. This product is vegan, non-GMO, and free from gluten, dairy, and soy. Each batch undergoes third-party testing for purity and potency, ensuring you receive a reliable supplement you can rely on.

What Is Pyridoxal-5-Phosphate (P-5-P)?

Vitamin B6 occurs in several forms, but only pyridoxal-5-phosphate (P-5-P) serves as the active coenzyme that the body can utilise immediately. Unlike pyridoxine hydrochloride (HCl), which requires conversion in the liver, P-5-P bypasses this step. This makes it particularly suitable for individuals with compromised liver function or genetic variations that hinder conversion. Each capsule provides 50 mg of pure P-5-P for efficient absorption.

How Does Vitamin B6 Support Neurotransmitter Production?

Vitamin B6 acts as a vital cofactor in the synthesis of several neurotransmitters. It is necessary for the production of GABA (gamma-aminobutyric acid), which promotes relaxation; the conversion of 5-HTP to serotonin, which influences mood and sleep; and the decarboxylation of levodopa to dopamine, critical for focus and motivation. By supplying the active coenzyme form, P-5-P contributes to healthy neurotransmitter levels, supporting balanced nervous system function.†

What Role Does Vitamin B6 Play in Energy Metabolism?

In addition to brain health, vitamin B6 is essential for energy production. It participates in amino acid and lipid metabolism, helping to convert food into usable energy. Furthermore, B6 is involved in homocysteine metabolism, working alongside folate and B12 to convert homocysteine into methionine. Maintaining healthy homocysteine levels contributes to cardiovascular health. By using P-5-P, you ensure optimal support for these metabolic pathways.†

Who Should Consider a P-5-P Supplement?

Individuals following vegan or vegetarian diets may have lower B6 intake from animal sources. Those with digestive issues or liver conditions that impair conversion of pyridoxine HCl may also benefit from the active form. Additionally, athletes and active individuals may require higher B6 for protein metabolism and energy production. As always, consult your health care professional before starting any new supplement.

Recommended Dosage and Safety

The suggested use is one capsule per day, providing 50 mg of P-5-P. The tolerable upper intake level for vitamin B6 is 100 mg per day from all sources. Do not exceed this amount unless directed by a health care provider. High-dose, long-term use (above 200 mg/day) may cause nerve toxicity. Discontinue use and consult a doctor if any adverse reactions occur. This product is a food supplement and should not be used as a substitute for a varied diet and a healthy lifestyle.

† These statements are made in line with EFSA-approved health claims.