Who Should Take a Vitamin B12 Supplement?
Vitamin B12 deficiency is more common than many realise, particularly amongst those following plant-based diets or with certain health conditions. While B12 is found naturally in animal products, supplements can provide a reliable alternative for those at risk. The following groups may particularly benefit from supplementation:
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Vegans and vegetarians — B12 is naturally present in animal-derived foods, so those avoiding meat, dairy, and eggs often require an external source.
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Older adults — Ageing can reduce stomach acid production, which is necessary for absorbing B12 from food.
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Individuals with digestive conditions — Crohn’s disease, coeliac disease, or pernicious anaemia can impair absorption.
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Those taking certain medications — Proton pump inhibitors and metformin may interfere with B12 status.
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People seeking cognitive and energy support — Even mild deficiency can lead to fatigue, brain fog, and mood changes.
Key Benefits of Active B12 & Folate
Klaire Labs Active B12 provides methylcobalamin and Metafolin®—the bioactive forms of vitamin B12 and folate. These forms are immediately available for the body to uses, avoiding the need for conversion. Key benefits supported by authorised health claims include:
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Contributes to normal energy-yielding metabolism — B12 and folate play a role in converting food into energy.
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Supports normal psychological function — These nutrients are involved in neurotransmitter synthesis, which can influence mood and mental clarity.
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Supports normal homocysteine metabolism — This is important for cardiovascular and nerve health*.
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Essential for normal cell division and DNA synthesis — Folate is particularly important during periods of rapid growth.
* These statements have not been evaluated by the Medicines and Health care products Regulatory Agency. This product is not intended to diagnose, treat, , or prevent any disease.
What Is Vitamin B12 and Why Do You Need It?
Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin that plays a critical role in numerous bodily functions. It is required for red blood cell production, nervous system maintenance, and DNA synthesis. The body cannot produce B12 on its own, so it must be obtained through diet or supplementation. Many individuals—particularly those with limited dietary intake or absorption issues—may not obtain sufficient amounts from food alone. A high-quality supplement like Klaire Labs Active B12 can help bridge this gap.
How to Choose the Best B12 Supplement
When selecting a B12 supplement, consider the form, dosage, and delivery method. Methylcobalamin is the preferred form for neurological support and is often recommended over cyanocobalamin because it requires no conversion in the body. Folate as Metafolin® (L-methylfolate) is the active form, making it ideal for individuals with MTHFR gene variations. The dissolvable lozenge format offers sublingual absorption, which can be beneficial for those with digestive issues or difficulty swallowing pills.
Recommended Dosage and How to Take Active B12
Each lozenge provides a potent dose of active B12 and folate. For best results, place one lozenge under the tongue and allow it to dissolve completely. This sublingual route delivers nutrients directly into the bloodstream via the oral mucosa, bypassing the digestive tract. Adults may take one lozenge daily or as directed by a health care professional. Always consult your practitioner before starting any new supplement, especially if you are pregnant, nursing, or taking medication.
Frequently Asked Questions About B12
Can you take too much B12?
Vitamin B12 is water-soluble, meaning excess amounts are typically excreted in urine. No tolerable upper intake level has been established, but it is wise to follow recommended dosages and consult a health care provider for personalized advice.
What is the difference between methylcobalamin and cyanocobalamin?
Methylcobalamin is the active coenzyme form that the body can uses immediately, while cyanocobalamin is a synthetic form that must be converted. For those with absorption or conversion issues, methylcobalamin is often preferred.
Is this supplement vegan?
Klaire Labs Active B12 lozenges are designed to be suitable for a variety of dietary preferences. Check the product label for specific dietary certifications.
Product Features
- Active B12 as methylcobalamin (1000 mcg) and active folate as Metafolin® (400 mcg L-methylfolate per serving)
- Dissolvable lozenge for rapid sublingual absorption
- Contributes to normal energy, mood, cognition, heart, and nerve health*
- Free from common allergens: gluten, dairy, soya, and artificial additives
- Trusted brand used by health care practitioners
Usage Instructions
Dissolve one lozenge under the tongue daily, or as directed by a health care professional. Store in a cool, dry place. Keep out of reach of children.
These statements have not been evaluated by the Medicines and Health care products Regulatory Agency. This product is not intended to diagnose, treat, , or prevent any disease.