Life Extension Optimised Folate – L-Methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – 1700 mcg DFE, 100 Vegetarian Tablets

What Is Optimised Folate?

Life Extension Optimised Folate delivers 1700 mcg DFE of L-methylfolate (5-MTHF), the biologically active form of vitamin B9. Unlike ordinary folic acid, this form is immediately available for your body to uses—no conversion needed. That makes it an excellent choice for supporting cardiovascular and cognitive health, particularly as you get older.

Folic Acid vs. Methylfolate: Which Is Better?

Standard folic acid is the synthetic version found in many supplements and fortified foods. It must be converted by the liver into active 5-MTHF, but up to 60% of the population have genetic variants that impair this process. L-methylfolate bypasses this step, supplying the active form directly. That's why Optimised Folate is a superior option for anyone with MTHFR gene variations or those seeking optimal absorption.

Health Benefits of Optimised Folate

Folate contributes to normal homocysteine metabolism, normal red blood cell formation, normal psychological function, and the reduction of tiredness and fatigue. By helping to maintain healthy homocysteine levels, this supplement supports cardiovascular health. It also plays a role in immune system function and is essential for normal cell division.

Who Should Consider This Supplement?

This supplement is ideal for adults aiming to support heart and brain health. It may be particularly helpful for individuals who struggle to convert folic acid due to MTHFR genetic variations. Women planning a pregnancy or during pregnancy may also benefit from adequate folate intake. Always consult a health care professional before starting any new supplement.

Recommended Dosage and Usage

Each tablet provides 1700 mcg Dietary Folate Equivalents (DFE), equivalent to 1000 mcg of folic acid. The recommended serving is one tablet daily, preferably with a meal. This dose is within the safe upper limit for supplementary folate (1000 mcg from folic acid or fortified foods). Do not exceed the recommended dose unless advised by your doctor.

Selecting a Quality Folate Supplement

When choosing a folate supplement, look for the active form (L-methylfolate or 5-MTHF) and a dosage that suits your needs. Life Extension uses premium raw ingredients and provides a Certificate of Analyse for every batch. Their products are non-GMO, gluten-free, and manufactured to high quality standards.

Potential Side Effects and Precautions

Folate supplements are generally well tolerated. However, high doses can mask a vitamin B12 deficiency, so ensure adequate B12 intake. Some people may experience mild digestive upset. If you have a medical condition or are taking medication, consult your health care provider before uses. Keep out of reach of children.

Frequently Asked Questions

Can I take this with other B vitamins?

Yes, Optimised Folate can be taken alongside other B vitamins. In fact, B12 and folate work synergistically to support homocysteine metabolism and red blood cell formation.

Is this suitable for vegans?

Yes, the tablets are vegetarian and free from animal-derived ingredients. They are also gluten-free and non-GMO.

How does this compare to standard folic acid?

Optimised Folate provides the active form, so it is more readily used by the body—especially if you have an MTHFR gene variant. It is a great choice for those who want to ensure efficient folate utilisation.

Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. This product is not intended to diagnose, treat, or prevent any disease. Always read the label and follow directions for uses. If you are pregnant, breastfeeding, taking any medication or under medical supervision, consult a doctor or health care professional before uses. Do not exceed the recommended daily dose. Keep out of reach of children.