Understanding the Synergy: How D3 and K2 Work Together
Vitamin D3 (cholecalciferol) stimulates the production of calcium-binding proteins in the gut, enhancing calcium absorption. Meanwhile, vitamin K2 activates two critical proteins: osteocalcin, which binds calcium to the bone matrix, and matrix GLA protein (MGP), which helps prevent calcium deposition in arteries.* This dual action makes the combination particularly valuable for maintaining bone density and arterial flexibility.* NatureWise utilises vegan D3 derived from lichen and vegan K2 (menaquinone-7) from fermented chickpeas, both in highly bioavailable forms.
Why Take Vitamin D3 and K2 Together?
Vitamin D3 and K2 work synergistically to support your body’s calcium balance. D3 helps your body absorb calcium from food, whilst K2 directs that calcium to where it’s most needed—your bones and teeth.* This partnership is essential for maintaining strong bones and supporting heart health.* Without sufficient K2, calcium may accumulate in soft tissues rather than your skeleton. By taking them together, you help ensure calcium is effectively utilised.*
Key Health Benefits of This Dual Formula
Each serving provides 10,000 IU of vitamin D3 and 200 mcg of vitamin K2. Notable benefits include:
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Bone Support: D3 aids calcium absorption, whilst K2 activates osteocalcin to incorporate calcium into bone.* This may help maintain bone density as you age.*
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Heart Health: K2 supports MGP, which helps prevent calcium build-up in blood vessel walls.* This promotes arterial flexibility and overall cardiovascular function.*
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Immune Support: Vitamin D3 contributes to normal immune function.* Adequate levels are linked to a healthy immune response.*
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Dental Health: Proper calcium utilisation also benefits teeth, as K2 directs calcium to tooth enamel.*
What Makes This NatureWise Formula Special?
This formula stands out for several reasons. Firstly, it employs VegaDELight D3, a natural vegan vitamin D3 sourced from sustainably harvested lichen—not lanolin or synthetic sources. The K2 comes from MenaquinGold, a patented, non-GMO form of menaquinone-7 from fermented chickpeas, backed by clinical research.* Secondly, the soft gel capsules are packed in organic MCT oil from coconuts, which enhances absorption of these fat-soluble vitamins and provides a clean energy source. Thirdly, the soft gel capsules are notably small and easy to swallow—a feature many users appreciate.* Each bottle provides a 90-day supply, making it a convenient daily addition to your wellness routine.
What to Look For in a D3 + K2 Supplement
When choosing a D3 and K2 supplement, consider the following:
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Form of D3: D3 (cholecalciferol) is more bioavailable than D2. Vegan D3 from lichen is an excellent plant-based option.
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Form of K2: MK-7 (menaquinone-7) has a longer half-life than MK-4, allowing for once-daily dosage. Look for natural, bioavailable sources.
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Dosage Ratio: Many studies undertake 1,000–5,000 IU D3 with 45–100 mcg K2, but higher doses like 10,000 IU D3 and 200 mcg K2 are available for those with greater needs. Consult a health care provider for personalised dosage.
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Quality and Purity: Choose supplements that are non-GMO, free of common allergens, and third-party tested. NatureWise products are manufactured in a cGMP-certified facility in the USA and undergo third-party quality audits.
Frequently Asked Questions
Is it safe to take 10,000 IU of vitamin D3 daily? For many adults, 10,000 IU is considered a high but safe dose, especially for those with low sun exposure or known deficiency. However, it’s best to cheque your vitamin D levels with a blood test and consult your health care provider before starting high-dose supplementation.
Can I take this supplement with other medications? Vitamin K2 can interact with blood thinners like warfarin (Coumadin). If you take anticoagulants, consult your doctor before using this product. Vitamin D3 may affect calcium metabolism in those with certain conditions.
When is the best time to take this supplement? Because it contains fat-soluble vitamins in MCT oil, take it with a meal containing fat for optimum absorption. Many people take it with breakfast or lunch.
Are the soft gel capsules easy to swallow? Yes—the soft gel capsules are small and oval-shaped, making them easy to swallow even for those who dislike large pills.
These statements have not been evaluated by the Medicines and Healthcare products Regulatory Agency. This product is not intended to diagnose, treat, or prevent any disease.