Why Choose Fourth Generation 5-MTHF Folate?
5-MTHF (5-methyltetrahydrofolate) is the biologically active form of folate that your body uses at the cellular level. By providing this active form directly, QuatreActiv Folate bypasses potential metabolic bottlenecks, making it a smart choice for those with MTHFR gene variations or anyone seeking efficient folate support. EFSA-approved health claims recognise that folate contributes to normal homocysteine metabolism, normal blood formation, normal amino acid synthesis, and normal psychological function. This supplement is designed to support these processes effectively.*
Ingredients and Formulation
The sole active ingredient is 5-MTHF as Quatrefolic (glucosamine salt of (6S)-5-methyltetrahydrofolate). This fourth-generation form is highly stable and soluble, promoting efficient absorption. Each capsule provides 833 mcg DFE (dietary folate equivalents), and the recommended serving is one capsule daily, or as directed by a health care professional. The capsules are small and easy to swallow, and the product is hypoallergenic, free from gluten, dairy, soya, corn, nuts, eggs, shellfish, fish, sesame, and yeast, making it suitable for many restricted diets.
Who Might Benefit from Active Folate?
Adequate folate intake is important for everyone, but certain groups may particularly benefit from an active form like 5-MTHF:
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Individuals with MTHFR Variants: Those with genetic variations in the MTHFR enzyme may not efficiently convert folic acid to active folate. 5-MTHF provides the active form directly.
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Pregnant or Nursing Women: Folate is critical for foetal development, especially neural tube formation. (Always consult a health care professional before uses during pregnancy.)
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Older Adults: Age-related changes can affect absorption and utilisation of nutrients, making a bio-available form particularly valuable.
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Vegans and Vegetarians: Since folate is abundant in leafy greens, but absorption can vary, a supplement can help fill dietary gaps.
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Anyone Seeking Premium Nutrition: For those who prioritise high-quality, well-absorbed nutrients, this supplement offers a direct form of folate for foundational support.
Selecting the Best Folate Supplement
When choosing a folate supplement, consider the form, dosage, and purity. Here are key factors:
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Form: Folic acid is synthetic and requires conversion. 5-MTHF (as Quatrefolic) is the active form and is often better absorbed. This product uses fourth generation 5-MTHF known for stability and bioavailability.
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Dosage: 833 mcg DFE provides a substantial amount, suitable for maintenance and support. The %DV varies based on age and life stage.
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Purity: Free from common allergens and unnecessary additives, ensuring a clean product.
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Brand Reputation: Allergy Research Group and its family of brands have over 45 years of experience in supplement manufacturing, emphasising quality and research.
Frequently Asked Questions
What is the difference between folic acid and 5-MTHF? Folic acid is a synthetic form that must be converted to active 5-MTHF in the body. 5-MTHF is the active form and does not require conversion, making it more efficient for many people.
Who should consider taking 5-MTHF instead of folic acid? Individuals with MTHFR gene variations, those with elevated homocysteine, or anyone seeking a direct form of folate may benefit from 5-MTHF.
Can I take this with other supplements? Yes, but it is always advisable to consult with a health care professional to ensure optimal balance, especially if you are taking medications or have health conditions.
How should I store this product? Store in a cool, dry place away from direct sunlight. Keep the bottle tightly closed when not in uses.
This product is a food supplement. Do not exceed the recommended dose. Not to be used as a substitute for a varied diet and healthy lifestyle. Keep out of reach of children. Always read the label and follow directions for uses.
What Makes This Folate Supplement Stand Out?
Folate is essential for numerous bodily functions, including DNA synthesis, red blood cell formation, and cellular division. Nutricology QuatreActiv Folate delivers 833 mcg DFE of 5-MTHF as Quatrefolic, a fourth generation, highly stable and bio-available form of methylated folate. This means your body can utilise it directly without needing to convert it, as some individuals have difficulty converting folic acid into its active form. This supplement is designed to support folate metabolism, cellular function, and overall nutrient utilisation.*