Our Daily Vites L-Methylfolate 1mg / 1000 mcg Maximum Strength Active Folate, 5-MTHF, Filler Free, Gluten-free, Non-GMO, 270 Vegetarian Capsules

Who Should Take L-Methylfolate?

This supplement is ideal for women planning pregnancy or who are pregnant, as it supports foetal development. It may also be useful for individuals with MTHFR gene variants who cannot efficiently convert folic acid to its active form. Others who may benefit include older adults, people with certain digestive conditions that impair nutrient absorption, and those following a vegan or vegetarian diet. Always consult with a health care professional before starting any new supplement, especially if you have a medical condition or are taking medication.

What is L-Methylfolate?

L-Methylfolate, also known as 5-MTHF, is the biologically active form of folate (vitamin B9). Unlike synthetic folic acid, L-methylfolate does not require conversion by the liver or the MTHFR enzyme, making it a superior choice for individuals with genetic variations that impair folate metabolism. This maximum strength supplement provides 1,000 mcg of pure, active folate per capsule, ensuring your body receives the form it can immediately uses for critical processes like DNA synthesis, cell division, and homocysteine regulation.

Health Benefits of L-Methylfolate

Adequate folate intake is essential for numerous bodily functions. L-methylfolate contributes to normal homocysteine metabolism, which is important for cardiovascular health. It also supports normal red blood cell formation, reducing the risk of megaloblastic anaemia. During pregnancy, sufficient folate intake is crucial for the developing baby's neural tube; the active form may be particularly beneficial for those with MTHFR mutations. Additionally, folate plays a role in neurotransmitter synthesis, supporting mood and cognitive function. * These statements are based on EFSA-approved health claims. This product is not intended to diagnose, treat, , or prevent any disease.*

Folic Acid vs. Methylfolate: Which Is Better?

Synthetic folic acid is commonly found in supplements and fortified foods, but it requires conversion by the liver and the MTHFR enzyme to become active. Approximately 40-60% of the population has a genetic variation that reduces this conversion efficiency. L-methylfolate bypasses these steps, providing the active form directly. This makes it a more reliable choice for ensuring adequate folate status, especially for those with MTHFR mutations. Our product uses the pure, bioidentical form of folate that your body recognises and utilises immediately.

How to Choose a Quality L-Methylfolate Supplement

When selecting a folate supplement, look for products that are third-party tested for purity and potency. Our Daily Vites L-Methylfolate is filler-free, gluten-free, and non-GMO. The capsules are vegetarian and the smallest available (size 4V), making them easy to swallow. We ensure each batch is independently tested to guarantee maximum effectiveness. Avoid supplements with unnecessary additives, and choose the active form (5-MTHF) for superior absorption.

Recommended Dosage

Each capsule contains 1 mg (1,000 mcg) of L-methylfolate. The reference nutrient intake (RNI) for folate in the UK is 200 mcg for adults, rising to 300 mcg during pregnancy. However, many health care practitioners recommend 1,000 mcg for pregnant women or those with MTHFR mutations. The upper safe level from supplements is 1,000 mcg per day. Our maximum strength formula provides a potent dose in a single, easy-to-swallow capsule. Take one capsule daily with food, or as directed by your doctor.

Potential Side Effects and Precautions

L-methylfolate is generally well tolerated, but some individuals may experience mild digestive discomfort. High doses of folate can mask a vitamin B12 deficiency, which is particularly important for older adults. If you have a history of B12 deficiency or pernicious anaemia, consult your doctor before taking this supplement. The tolerable upper intake is 1,000 mcg from supplements; do not exceed without medical supervision.

Frequently Asked Questions

Can I take this during pregnancy? Yes, this supplement is ideal for pregnancy. The active form may be especially beneficial for supporting foetal neural tube development. Supplementing with folic acid increases maternal folate status. Low maternal folate status is a risk factor for the development of neural tube defects in the developing foetus.

Is this better than folic acid? For many people, especially those with MTHFR gene variants, L-methylfolate is more effective because it is already in the active form.

How many capsules per serving? One capsule provides 1,000 mcg. The bottle contains 270 servings.

Is this product non-GMO and gluten-free? Yes, it is certified non-GMO and gluten-free, with no fillers or allergens.