ProHealth Longevity TMG Pro 500g Bulk Powder (Trimethylglycine - Betaine Anhydrous) – Methylation Support

Why Choose ProHealth Longevity TMG Pro?

ProHealth Longevity has been a trusted name in supplements since 1988. Their TMG Pro is a pure, additive-free powder that provides 500g of betaine anhydrous per container. Every batch undergoes rigorous third-party testing for purity and potency, with full results published online. Manufactured in the UK in GMP-certified facilities, this product aligns with the highest standards of quality and transparency.

How Does TMG Support Methylation and Homocysteine Levels?

The body relies on methyl donors like TMG to convert homocysteine—an amino acid that can be harmful in excess—into methionine, a building block for proteins and other molecules. This conversion helps maintain homocysteine within a healthy range, supporting arterial flexibility and overall cardiovascular function. For individuals with genetic polymorphisms that impair natural methylation, TMG can be particularly valuable. As recognized by the European Food Safety Authority (EFSA), TMG contributes to normal homocysteine metabolism and normal energy-yielding metabolism.

What Is TMG (Trimethylglycine) and Why Does It Matter?

Trimethylglycine, also known as TMG or betaine anhydrous, is a naturally occurring amino acid derivative found in foods like beetroot, spinach, and whole grains. It plays a centre role in the body's methylation cycle—a biochemical process essential for DNA repair, cellular energy production, metabolism, and liver detoxification. As we age, or in the presence of common genetic variations (such as MTHFR mutations), methylation efficiency can decline. Supplementing with TMG helps replenish the methyl pool, supporting these vital functions.

How to Incorporate TMG Powder Into Your Routine

TMG powder has a mildly sweet, beet-like flavour and mixes easily into water, juice, or smoothies. A typical serving size is 500–1000 mg per day, whilst individual needs may vary. Many longevity experts recommend taking TMG alongside NMN (nicotinamide mononucleotide) to support a healthy methyl pool, especially for those focused on cellular ageing and energy. As with any supplement, consult your health care provider before starting a new regimen.

Key Benefits of TMG Supplementation

TMG offers a range of potential benefits when used as part of a balanced diet and healthy lifestyle:

• Methylation Support: TMG contributes to normal homocysteine metabolism and normal energy-yielding metabolism as approved by EFSA.
• Healthy Homocysteine Metabolism: By aiding the conversion of homocysteine to methionine, TMG helps maintain already-normal homocysteine levels, which is important for cardiovascular health.
• Normal Energy Production: TMG contributes to normal energy-yielding metabolism, supporting mitochondrial function.
• Liver Detoxification: TMG is involved in the body's methylation pathways, which support normal liver function.

Frequently Asked Questions About TMG

Can TMG help with energy levels?

By supporting methylation and mitochondrial function, TMG contributes to normal energy metabolism. However, individual results can vary, and it should not be used as a stimulant.

Is TMG safe for long-term uses?

TMG is generally well tolerated when taken at recommended dosages. Some individuals may experience mild digestive upset. It is always best to start with a lower dose and see how your body responds.

Do I need to take TMG with NMN?

While not required, many people combine TMG with NMN because increased NAD+ production can deplete methyl groups. TMG helps replenish these groups, supporting balanced methylation.

Quality You Can Trust

ProHealth Longevity maintains a Better Business Bureau A+ rating and has been a leader in the supplement industry for over three decades. Their TMG Pro is triple-tested for purity and potency by independent labs, with transparent results accessible online. This commitment ensures you receive a high-quality product free from contaminants.

*These statements have not been evaluated by the European Medicines Agency or the Food Standards Agency. This product is not intended to diagnose, treat, , or prevent any disease.