Skip to product information
1 of 9

Pure SAM E Supplement 400mg – with Vitamin B12

Pure SAM E Supplement 400mg – with Vitamin B12

Regular price £41.88 GBP
Sale price £41.88 GBP Regular price
Save % Sold out

HOT PRODUCT | LOW STOCK

Carefully selected from trusted wellness brands

Free worldwide delivery

Secure checkout

Buy More Save More!

Pure SAM E Supplement 400mg – with Vitamin B12

Regular price £41.88
Sale price £41.88 Regular price
Save % Sold out
  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Visa

Tracked worldwide delivery. Estimated arrival between - and -.

Top Ingredients in This Formula

The primary ingredient is S-adenosylmethionine (SAM-e) at 400 mg per serving. SAM-e is derived from methionine and adenosine triphosphate and serves as a critical methyl donor in the body. This formula also contains vitamin B12 (as cyanocobalamin), which contributes to normal energy-yielding metabolism and the normal functioning of the nervous system. Both ingredients work synergistically to promote overall vitality.

What Is Pure SAM E 400mg?

Pure SAM E 400mg delivers a potent dose of S-adenosylmethionine (SAM-e), a compound naturally produced by your body that plays a key role in methylation processes. This supplement is paired with vitamin B12 to help support energy metabolism and neurological health. Each serving provides 400 mg of SAM-e in an easy-to-swallow capsule, making it a convenient addition to your daily routine.

Who Can Benefit from SAM-e?

Adults looking to maintain healthy energy levels, nervous system function, or methylation support may find SAM-e helpful. It is also popular amongst those seeking a natural nootropic to support focus and memory. Because SAM-e levels naturally decline with age, supplementation can be particularly beneficial for older adults. As with any supplement, consult a health care professional before uses, especially if you have medical conditions or take medications.

Key Benefits of SAM-e Supplementation

SAM-e is involved in methylation, a process essential for DNA repair, neurotransmitter synthesis, and detoxification. The formula includes vitamin B12, which contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue. Benefits associated with SAM-e include maintaining joint flexibility and supporting normal liver function, but these are not authorised health claims under UK law.

  • Energy Support: Vitamin B12 helps convert food into energy, reducing tiredness and fatigue.
  • Nervous System Function: Vitamin B12 supports normal neurological function, which may help maintain mental clarity and focus.
  • Methylation Support: SAM-e is a key methyl donor, supporting the body’s natural detoxification processes.
  • Joint Flexibility: SAM-e is traditionally used to help maintain joint comfort and flexibility when taken consistently.

How to Choose a Quality SAM-e Supplement

When selecting a SAM-e product, consider the form and potency. Pure SAM E 400mg uses a stable, enteric-coated form of S-adenosylmethionine to ensure optimal absorption. Look for supplements that are third-party tested for purity and potency. This product is manufactured in a facility that follows good manufacturing practices (GMP). Check the label for added ingredients like vitamin B12, which can enhance the benefits.

FAQs About SAM-e

How should I take Pure SAM E 400mg?

Take one capsule daily with or without food, preferably on an empty stomach for better absorption. Do not exceed the recommended dosage.

How long does it take to feel results?

Individual experiences vary. Some users notice energy improvements within a few days, while joint benefits may take several weeks.

Are there any side effects?

SAM-e is generally well tolerated. Some people may experience mild digestive upset or headache. If you have bipolar disorder or are taking antidepressants, consult your doctor before uses.

This product is a food supplement. It is not intended to diagnose, treat, or prevent any disease. Always read the label and follow directions for uses.

Worldwide Delivery

Orders are prepared with clear worldwide delivery expectations from the product page through dispatch. Delivery estimates are shown before checkout where available, and tracking details are sent after the order leaves fulfilment so customers can follow the parcel and plan around the expected arrival window.

Returns and support

UK Vitality Vitamins offers straightforward post-purchase support with a clear returns process. Please check the store returns policy before sending an item back, as final eligibility may depend on product condition, packaging integrity and whether the return request is started within the stated return window.

How to choose

Use the product description, ingredient list, serving information and available variants to compare supplement options. Always check the full ingredient list, directions for use and any allergen information on the product packaging before taking any food supplement.

Ingredients and important information

Ingredient lists and formulations may vary by batch or supplier. Always check the product packaging for the most up-to-date information. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily intake. If you are pregnant, nursing, taking medication or have a medical condition, consult your healthcare professional before use.

View full details
  • Tracked worldwide delivery

    Clear delivery messaging for shoppers worldwide.

  • Secure checkout

    Secure checkout.

  • Clear returns

    Returns information is written plainly before purchase.

  • Trusted brands

    Carefully selected supplements from established wellness brands.

Supplement guide

Pure SAM E Supplement 400mg – with Vitamin B12 at UK Vitality Vitamins

Top Ingredients in This FormulaThe primary ingredient is S-adenosylmethionine (SAM-e) at 400 mg per serving. SAM-e is derived from methionine and adenosine triphosphate and serves as a critical methyl donor in the bod...

Category Blended Vitamin & Mineral Supplements
Delivery area Worldwide
Checkout Secure checkout
Brand Phytoral
Price £41.88
Availability In stock
energy supplementfood supplementjoint flexibilitymemory supportmethylationnervous system supportPhytoralS-adenosylmethionineSAM-evitamin B12

How to choose if this supplement fits your routine

Read the ingredient list, check the serving size and directions for use. Consider the supplement form (tablet, capsule, liquid) and whether it suits your dietary requirements. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

What UK Vitality Vitamins shows before checkout

Every product page displays price, availability, variant choices, ingredient information, directions for use, allergen details, worldwide delivery expectations and secure checkout — so you can make an informed decision quickly.

Questions about Pure SAM E Supplement 400mg – with Vitamin B12

Is Pure SAM E Supplement 400mg – with Vitamin B12 available with worldwide delivery?

Yes. This product is currently available on UK Vitality Vitamins with free worldwide delivery.

How should I compare this with similar supplements?

Compare the active ingredients, serving size, number of servings per container, supplement form, brand reputation and price per serving. Check allergen information if relevant to your dietary needs.

Where can I find delivery and returns information?

Delivery information is shown near the add to basket area. Returns guidance is available on the product page and full terms are covered in the store returns policy.

Supplement shopping with clarity

UK Vitality Vitamins product pages display ingredients, directions, allergen details and delivery information clearly — so you can compare supplements and make informed choices quickly.