Pyridoxine P5P - Vitamin B6 (Pyridoxal Phosphate) 60 Capsules

Recommended Dosage

Discover Nutricology Allergy Research — Getting the right amount of vitamin B6 is essential for overall health, and the active form P5P offers enhanced bioavailability. The typical daily intake recommended for adults is around 1.3–2.0 mg, whilst many supplements provide higher doses ranging from 25 mg to 100 mg per serving. The tolerable upper intake level (UL) for adults is set at 100 mg per day from food and supplements combined. As with any supplement, it is wise to consult a health care professional to determine the appropriate dosage for your individual needs.

What Is Pyridoxal Phosphate (P5P)?

Pyridoxal phosphate, often abbreviated as P5P, is the biologically active coenzyme form of vitamin B6. Unlike the more common pyridoxine hydrochloride (HCl) found in many supplements, P5P does not require conversion by the liver. This makes it particularly beneficial for individuals with liver conditions or genetic variations that impair vitamin B6 activation. As the active form, P5P participates directly in over 100 enzymatic reactions, including amino acid metabolism, neurotransmitter synthesis, and homocysteine regulation.

Health Benefits of Vitamin B6

Vitamin B6, in its active P5P form, contributes to a range of essential bodily functions:

• Energy Metabolism: Vitamin B6 contributes to normal energy-yielding metabolism, helping your body convert food into usable energy.
• Homocysteine Regulation: Along with vitamin B12 and folate, P5P contributes to normal homocysteine metabolism, which supports cardiovascular health.
• Nervous System Function: As a cofactor in neurotransmitter production—including serotonin, dopamine, and GABA—vitamin B6 contributes to normal psychological function and nerve signalling.
• Immune Support: The vitamin contributes to the normal function of the immune system by influencing the production and activity of immune cells.

How to Choose a Vitamin B6 Supplement

When selecting a vitamin B6 supplement, consider the form, dosage, and quality. Pyridoxal phosphate (P5P) is often preferred for its bioavailability and immediate activity. Look for products from reputable brands that prioritise purity and potency. Nutricology Allergy Research Group's Pyridoxine P5P is formulated with high-quality ingredients and undergoes rigorous testing to ensure consistency. This supplement is suitable for those seeking targeted support for energy, nervous system health, and metabolic function.

Potential Side Effects & Safety

Vitamin B6 is generally well-tolerated when taken within recommended limits. However, prolonged intake of very high doses (exceeding 200 mg per day) has been associated with peripheral neuropathy, a condition characterised by numbness or tingling in the extremities. To minimise risk, avoid exceeding the UL of 100 mg daily unless specifically directed by a physician. P5P itself may have a lower risk of toxicity compared to pyridoxine HCl, but caution is still advised. Always discuss supplementation with your health care provider, especially if you are pregnant, nursing, or taking medications.

This product is a food supplement and should not be used as a substitute for a varied diet and healthy lifestyle.