Key Benefits of Active Folate B12 Synergy
This synergistic combination of methylated B12 and folate provides targeted support for several aspects of health. Vitamin B12 contributes to normal energy-yielding metabolism, helping your body convert food into usable energy. Folate contributes to normal psychological function and the reduction of tiredness and fatigue. The bioactive forms used here—MecobalActive™ (methylcobalamin) and Quatrefolic® (5-MTHF)—are immediately available for the body to uses, bypassing conversion barriers that can hinder effectiveness in some individuals.
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Energy support: B12 and folate contribute to normal energy metabolism and the reduction of fatigue.*
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Cognitive function: These nutrients support normal nervous system function and mental performance.*
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Mood balance: Folate plays a role in the synthesis of mood-regulating neurotransmitters, while B12 supports neurological health.*
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Cardiovascular health: Both B12 and folate help maintain normal homocysteine levels, which supports heart health as part of a balanced diet.*
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Cellular health: They are essential for normal DNA synthesis and red blood cell formation.*
*These statements are based on EFSA-approved health claims. Food supplements should not be used as a substitute for a varied diet and healthy lifestyle.
Who Should Take This Supplement?
This lozenge is ideal for individuals looking to support their energy levels, mental clarity, and overall wellbeing with a high-quality, bioactive B12 and folate formula. It is particularly beneficial for:
- People with MTHFR mutations or methylation issues who require pre-methylated nutrients.
- Vegans and vegetarians, who may have lower dietary intake of B12.
- Older adults, as B12 absorption can decline with age.
- Those experiencing occasional tiredness or brain fog seeking nutritional support.
- Anyone who prefers a convenient, pleasant-tasting alternative to pills.
As with any supplement, consult a health care professional before uses, especially if you are pregnant, nursing, taking medication, or have a medical condition.
Product Features
- Bioactive B12 (MecobalActive™) – 2500 mcg per lozenge
- Methylated folate (Quatrefolic®) – 1700 mcg per lozenge
- Fast-dissolving, naturally flavoured lozenge
- Physician formulated for superior bioavailability
- Free from gluten, soya, and dairy
- Vegan-friendly
What Is Active Folate B12 Synergy and Why Do You Need It?
Vitamin B12 and folate are essential nutrients that work together to support energy metabolism, cognitive function, and overall cellular health. Many supplements uses synthetic forms that require conversion in the body—a step that can be inefficient for some people. RetzlerRx Active Folate B12 Synergy Lozenge delivers both nutrients in their bioactive forms: MecobalActive™ B12 (methylcobalamin) and Quatrefolic® (5-MTHF), the active form of folate. This means your body can uses them immediately without needing to convert them, making it an excellent choice for those with genetic variations (like MTHFR) that affect nutrient metabolism.
Each lozenge provides 2500 mcg of methylcobalamin—a highly absorbable form that supports nerve health and red blood cell production—along with 1700 mcg of 5-MTHF, which plays a key role in methylation, mood regulation, and DNA synthesis. Developed by physicians, this formula is designed for maximum bioavailability and effectiveness.
How to Choose the Best B12 and Folate Supplement
Not all B12 and folate supplements are the same. The key differentiator is the form of the nutrient. Many products uses cyanocobalamin (synthetic B12) and folic acid (synthetic folate), which require enzymatic conversion in the body. This can be problematic for people with certain genetic polymorphisms (e.g., MTHFR variants) or digestive issues. RetzlerRx uses the active forms: MecobalActive™ (methylcobalamin) and Quatrefolic® (5-MTHF). These forms are immediately bio-available, bypassing conversion barriers. Additionally, the lozenge format allows for sublingual absorption, which can be more effective for those with poor intestinal absorption. This product is also free from common allergens like gluten, soya, and dairy, making it suitable for many dietary preferences.
Recommended Dosage and Usage
For best results, take one lozenge daily or as directed by your health care professional. Place the lozenge in your mouth and allow it to dissolve completely before swallowing. It can be taken with or without food. The high potency (2500 mcg B12 and 1700 mcg folate) is well within safe limits, as B12 is water-soluble and excess is excreted. However, individual needs vary, so it is advisable to consult a practitioner to determine the appropriate dosage for your specific situation.
Frequently Asked Questions
Can I take this if I have a MTHFR mutation?
Yes, this product is specifically designed with methylated forms (methylcobalamin and 5-MTHF) that are directly usable by individuals with MTHFR variations, bypassing the need for conversion.
Is this product vegan?
Yes, the lozenges are vegan-friendly and contain no animal-derived ingredients.
How does the lozenge taste?
The lozenges have a natural, pleasant flavour without artificial sweeteners or colours, making them easy to take daily.
Can I take more than one lozenge per day?
While the formula is potent at one lozenge, you may follow your health care provider's recommendation. Do not exceed the suggested dose without professional advice.
Usage Instructions
Take one lozenge daily. Allow to dissolve in the mouth. For optimal absorption, avoid swallowing whole. Store in a cool, dry place. Keep out of reach of children. Do not uses if seal is broken. This product is not a substitute for a balanced diet.
Food supplements should not be used as a substitute for a varied diet and healthy lifestyle.