THORNE Sacro-B: Saccharomyces boulardii Probiotic for Gut Health

Why Choose Thorne Sacro-B?

Thorne is a brand trusted by over 100 professional sports teams and is the #1 most recommended clinical brand by both consumers and health care practitioners, according to a 2026 independent survey. This reputation rests on a foundation of quality and transparency. Sacro-B is third-party certified, undergoing rigorous testing for potency and purity. The shelf-stable formulation ensures you always have a potent probiotic on hand—no refrigeration required. Whether you're an athlete, a frequent traveller, or simply someone who values digestive wellness, Sacro-B offers reliable support you can count on.

What Is THORNE Sacro-B?

Looking to support your digestive health? Thorne Sacro-B is a premium probiotic supplement featuring Saccharomyces boulardii, a clinically studied yeast strain known for its ability to promote a balanced gut environment. Unlike bacterial probiotics, this unique yeast-based formula is naturally resistant to stomach acid and antibiotics, making it a versatile addition to your wellness routine. Each easy-to-swallow capsule delivers 5 billion colony-forming units (CFUs) of active culture, and the shelf-stable design means no refrigeration is needed—ideal for travel or daily use. This product is third-party certified, ensuring that what's on the label matches what's in the bottle, with no unsafe levels of contaminants.

How Sacro-B Supports Digestive Health

A healthy gut relies on a balanced microbiome. Saccharomyces boulardii works by supporting the growth of beneficial gut flora while helping to maintain the integrity of the intestinal barrier. Research suggests it may help reduce the frequency and duration of occasional diarrhoea, such as that associated with travel or antibiotic use. By promoting a healthy microbial environment, Sacro-B helps your digestive system function smoothly. As a transient probiotic, it does not colonise permanently but provides support while passing through the digestive tract.

FAQs About Sacro-B and Saccharomyces boulardii

Is Saccharomyces boulardii safe?

Yes, for most healthy individuals. Saccharomyces boulardii has a long history of safe use as a probiotic. It is generally well-tolerated, whilst mild bloating may occur initially. If you have a weakened immune system or are critically ill, consult your doctor before use.

How is it different from bacterial probiotics?

Unlike bacterial probiotics (e.g., Lactobacillus), Saccharomyces boulardii is a yeast. It is naturally resistant to antibiotics and stomach acid, making it a good choice when you're taking antibiotics. It does not colonise the gut but provides transient support.

Does it need to be refrigerated?

No! Sacro-B is shelf-stable, so you can store it at room temperature. This makes it convenient for travel and everyday use.

How should I take Sacro-B?

Take one capsule daily with or without food, or as directed by your health care practitioner. You can open the capsule and mix the powder into cool or lukewarm food or drink. Avoid hot liquids as they may harm the live cultures.

Supporting the Body's Natural Defences

A healthy gut contributes to overall wellbeing, including the body's natural defences. Saccharomyces boulardii encourages the production of secretory IgA (sIgA), an antibody that plays a key role in the gastrointestinal tract. By nurturing gut-associated lymphoid tissue (GALT), this probiotic helps maintain a balanced immune response. Please note: this product is not intended to diagnose, treat, , or prevent any disease. Food supplements should not be used as a substitute for a balanced diet and healthy lifestyle.

Who Should Consider Taking Sacro-B?

Sacro-B is ideal for anyone looking to support their digestive health. It is particularly beneficial for individuals experiencing occasional digestive upset, those taking antibiotics (which can disrupt gut flora), and travellers exposed to new bacteria. Vegans and vegetarians will appreciate that the capsules are free from animal-derived ingredients. However, those with compromised immune systems or centre venous catheters should consult a health care provider before use, as yeast probiotics require special consideration in immunocompromised individuals.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, , or prevent any disease.