THORNE Vitamin B12 – Methylcobalamin – 60 Capsules

Who Should Consider a Vitamin B12 Supplement?

Vitamin B12 is essential for nerve function, red blood cell formation, and energy metabolism, yet certain groups are at higher risk of insufficiency. Vegans and vegetarians often lack dietary B12 as it is mainly found in animal products. Older adults may have reduced stomach acid, hindering absorption from food. Individuals with digestive conditions like Crohn’s, coeliac disease, or pernicious anaemia—or those who have undergone weight loss surgery—may also benefit. Additionally, long-term use of metformin or proton pump inhibitors can deplete B12 levels. THORNE Vitamin B12 offers a reliable, high-quality option to help fill these gaps.

What Is Vitamin B12 and Why Is It Important?

Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin that plays a critical role in nerve function, red blood cell formation, and DNA synthesis. It also supports energy metabolism by helping convert food into usable energy. Unfortunately, many people struggle to get enough B12 from diet alone. THORNE Vitamin B12 delivers 1 mg (1000 mcg) of methylcobalamin per capsule—the naturally occurring, bioactive form that your body can use immediately without needing to convert it from synthetic sources.

Key Benefits of Vitamin B12

Supports Normal Homocysteine Metabolism – Vitamin B12 helps maintain homocysteine levels within a normal range, contributing to cardiovascular health.

Promotes Healthy Nerve Function – As methylcobalamin, this B12 is directly available for myelin production, the protective sheath around nerves. Healthy myelin supports efficient nerve signalling.

Supports Red Blood Cell Formation – B12 is essential for proper red blood cell development, aiding oxygen transport throughout the body.

Contributes to Normal Energy-Yielding Metabolism – B12 helps reduce tiredness and fatigue by supporting energy production.

Aids Methylation – Methylation is a fundamental biochemical process affecting gene expression, detoxification, and neurotransmitter production. Methylcobalamin is a key cofactor in this pathway.

How to Choose the Best B12 Supplement

Not all B12 supplements are created equal. Two common forms are cyanocobalamin and methylcobalamin. Cyanocobalamin is synthetic and must be converted in the liver to active forms. Methylcobalamin is already active, making it more efficient—especially for those with methylation issues or who prefer a bioactive form. Dosage matters: 1000 mcg (1 mg) is a standard maintenance dose for most individuals, while higher doses may be recommended for deficiency correction. Delivery form also affects absorption; while capsules are convenient, sublingual options bypass the stomach for direct absorption. THORNE use methylcobalamin in a simple capsule, free from gluten, dairy, and soy, and third-party tested for purity and potency.

Recommended Dosage and How to Take B12

For adults, the typical dosage is one capsule daily with food, unless otherwise directed by a health care professional. Each THORNE capsule provides 1 mg (1000 mcg) of methylcobalamin, a level that supports sufficiency for most people. B12 is water-soluble, so excess is excreted; however, always follow the label and consult your practitioner if you have specific health concerns.

Frequently Asked Questions

Can you take too much B12? Vitamin B12 has a very low toxicity risk. The body excretes excess through urine. However, it is best to stick to recommended doses unless advised by a health care provider.

Is methylcobalamin better than cyanocobalamin? For many people, methylcobalamin is preferred because it is the active form, especially for supporting methylation and nerve health. It may be more beneficial for individuals with certain genetic variations in the MTHFR gene.

Can I take this on an empty stomach? While B12 can be taken with or without food, taking it with a meal may improve absorption if you have sensitive digestion.

Product Highlights

• Active B12: 1 mg methylcobalamin per capsule
• Third-Party Tested: Tested for purity and label accuracy
• Free From: Gluten, dairy, soy, and artificial ingredients
• Trusted Brand: Recommended by health care practitioners and used by over 100 professional sports teams

This product is a food supplement and should not be used as a substitute for a varied diet and healthy lifestyle. Always read the label and follow directions for use.