Understanding Vitamin B12 and Methyl Folate
Vitamin B12 (cobalamin) and folate (vitamin B9) are essential B vitamins that work together to support a range of bodily functions. B12 contributes to normal nerve tissue health, brain function, and red blood cell formation, while folate plays a key role in DNA synthesis and cell division. Together, they help maintain normal energy levels, support a healthy nervous system, and promote cardiovascular health. Vital Nutrients Vitamin B12 & Methyl Folate provides these nutrients in their most bioactive forms—methylcobalamin and L-5-methyltetrahydrofolate (5-MTHF)—so your body can use them immediately without needing to convert synthetic forms. This makes it an excellent choice for individuals with genetic variations (like MTHFR) that impair folate conversion.
Key Benefits of Methylated B12 and Folate
Vitamin B12 contributes to normal energy-yielding metabolism by helping convert food into energy. It also contributes to normal function of the nervous system and normal psychological function. Folate contributes to normal amino acid synthesis and homocysteine metabolism, which is important for cardiovascular health. Together, they aid in the formation of red blood cells and support the normal function of the immune system. Because Vital Nutrients use methylated forms, these benefits are enhanced—your body can utilise the nutrients without relying on the often-compromised methylation pathway.†
How to Choose the Best B12 Supplement: Why Methylated Forms Matter
Not all B12 and folate supplements are created the same. The most common form of B12 in supplements is cyanocobalamin, which contains a cyanide molecule that must be removed by the liver. Methylcobalamin, used here, is the naturally occurring bioactive form that is readily used by the body for nerve function and detoxification. Similarly, folic acid is the synthetic form of folate that requires multiple enzymatic steps to become active—steps that are inefficient in many people. This product provides L-5-MTHF, the active form that bypasses these conversion issues. Combined with third-party testing for purity and potency, and a hypoallergenic, vegan, non-GM formula, this supplement stands out for those seeking optimal absorption and efficacy.
Who Should Consider This B12 and Folate Supplement?
This supplement is ideal for vegans and vegetarians, as B12 is naturally found only in animal products. Older adults may also benefit, as stomach acid production declines with age, reducing B12 absorption from food. Those with digestive conditions such as coeliac disease or Crohn's disease, or those taking medications like metformin or proton pump inhibitors, may have increased needs. Additionally, anyone seeking to support their nervous system, energy metabolism, or red blood cell production can benefit from this high-potency, methylated formula. The inclusion of methylfolate makes it particularly suitable for those with MTHFR polymorphisms, who may struggle to convert folic acid into its active form.
Recommended Dosage and How to Take This Supplement
The suggested serving is one capsule daily, or as directed by your health care professional. Each capsule provides 800 mcg of L-5-MTHF and 1000 mcg (1 mg) of vitamin B12 as methylcobalamin. This dosage is well within safe limits and suitable for daily use, even for those with increased needs. For best absorption, take with food and a full glass of water. If you are pregnant, nursing, taking medication, or have a medical condition, consult your doctor before use. Store in a cool, dry place away from direct sunlight.
Frequently Asked Questions
Can you take too much B12 or methylfolate? B12 is water-soluble, so excess is excreted in urine; however, very high doses are not recommended without medical supervision. Methylfolate is generally well-tolerated, but some individuals may experience mild digestive upset. Always follow the recommended dosage.
Is this supplement suitable for vegans? Yes, it is 100% vegan and free from animal-derived ingredients, gluten, dairy and soy.
How long does one bottle last? With 100 capsules per bottle, a daily serving of one capsule provides a 100-day supply.
Is this product third-party tested? Yes, Vital Nutrients performs rigorous third-party laboratory testing on raw ingredients and finished products to ensure purity and potency.
Product Highlights
- Bioactive methylcobalamin (B12) and L-5-MTHF (folate) for superior absorption
- 800 mcg methylfolate and 1000 mcg vitamin B12 per serving
- Vegan, non-GM, hypoallergenic – free from gluten, dairy and soy
- Third-party tested for purity and potency
- Trusted by health care practitioners for over 30 years
Usage Instructions
Take one capsule daily with a meal, or as directed by your health care practitioner. Do not exceed recommended dosage. Keep out of reach of children.
† The health claims in this product have been authorised by the European Food Safety Authority (EFSA) and are featured on the EU Register of nutrition and health claims. This product is a food supplement and should not be used as a substitute for a varied diet and a healthy lifestyle.