Skip to product information
1 of 7

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings

Regular price £124.60 GBP
Sale price £124.60 GBP Regular price
Save % Sold out

HOT PRODUCT | LOW STOCK

Carefully selected from trusted wellness brands

Free worldwide delivery

Secure checkout

Buy More Save More!

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings

Regular price £124.60
Sale price £124.60 Regular price
Save % Sold out
  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Visa

Tracked worldwide delivery. Estimated arrival between - and -.

Key Ingredients: SAM-e and TMG

SAM-e (400 mg): S-Adenosylmethionine is a naturally occurring compound that acts as a methyl donor in over 100 biochemical reactions, including DNA methylation, protein modification, and phospholipid synthesis. It plays a role in the production of neurotransmitters such as serotonin and dopamine, and helps maintain cell membrane fluidity. XYMOGEN use a stable, enteric-coated form to support optimal absorption.

TMG (600 mg): Trimethylglycine, also known as betaine, is a methyl donor that helps recycle homocysteine to methionine, thereby supporting the body’s natural antioxidant defences. It works synergistically with SAM-e to sustain methylation cycles and contributes to liver function. TMG is also involved in osmoregulation and cellular hydration.

Together, these ingredients provide a comprehensive approach to methylation support, addressing both methyl donation and recycling.

What Is SAM-e & TMG?

S-Adenosylmethionine (SAM-e) and Trimethylglycine (TMG) are two naturally occurring substances that play integral roles in methylation—a fundamental biochemical process involved in DNA synthesis, detoxification pathways, and neurotransmitter production. XYMOGEN SAM-e & TMG delivers 400 mg of SAM-e and 600 mg of TMG per serving to support these critical pathways. This formulation is designed for individuals seeking targeted methylation support as part of their daily wellness routine.

Key Benefits of SAM-e & TMG Supplementation

Methylation is essential for numerous physiological functions, and maintaining adequate levels of SAM-e and TMG may help support optimal cellular and metabolic health.*

  • Cellular & Metabolic Function: SAM-e and TMG play a role in biochemical pathways that underpin cell health, nutrient metabolism, and energy processes.*
  • Neurotransmitter & Liver Support: SAM-e contributes to the synthesis of neurotransmitters such as serotonin and dopamine, while TMG supports glutathione production, which aids the liver’s natural detoxification pathways.*
  • Glutathione Production: TMG acts as a methyl donor to help recycle homocysteine to methionine, supporting the body’s antioxidant defences.*

These benefits make SAM-e & TMG a valuable addition for those refocusing on liver health, mood balance, and overall vitality.

Why Choose XYMOGEN SAM-e & TMG?

XYMOGEN is a trusted brand amongst health care professionals, known for evidence-based formulations. This supplement is crafted with allergen-aware purity: it is free from gluten, GMOs, dairy, soy, peanuts, egg, and shellfish, making it suitable for a wide range of dietary needs. It is also vegan and comes in a pleasant lemon flavour. Each pack provides 30 servings, offering a convenient month’s supply. XYMOGEN champions integrative health, empowering individuals and practitioners with high-quality supplements.

Frequently Asked Questions

Who can benefit from SAM-e & TMG?

Individuals with methylation imbalances, those supporting liver detoxification, or anyone looking to maintain healthy neurotransmitter levels may find this supplement beneficial. It is also popular amongst those with MTHFR gene variations that affect methylation efficiency.

How should I take SAM-e & TMG?

The recommended serving is one capsule daily, preferably on an empty stomach. Always follow the dosage instructions on the label or as advised by your health care practitioner.

Are there any side effects?

SAM-e and TMG are generally well-tolerated. Some individuals may experience mild gastrointestinal discomfort or nausea. It is advisable to start with a lower dose and increase gradually. Consult your health care provider before use, especially if you are pregnant, nursing, or taking medication.

How to Incorporate SAM-e & TMG Into Your Routine

For best results, take XYMOGEN SAM-e & TMG consistently as part of your daily supplement regimen. It can be taken alongside a balanced diet and other supplements, but avoid combining with high-dose folate or other methyl donors unless directed by a professional. Store in a cool, dry place away from direct sunlight.

This product is a food supplement and should not be used as a substitute for a varied diet and healthy lifestyle. If you are pregnant, nursing, or taking medication, consult your health care professional before use.

Worldwide Delivery

Orders are prepared with clear worldwide delivery expectations from the product page through dispatch. Delivery estimates are shown before checkout where available, and tracking details are sent after the order leaves fulfilment so customers can follow the parcel and plan around the expected arrival window.

Returns and support

UK Vitality Vitamins offers straightforward post-purchase support with a clear returns process. Please check the store returns policy before sending an item back, as final eligibility may depend on product condition, packaging integrity and whether the return request is started within the stated return window.

How to choose

Use the product description, ingredient list, serving information and available variants to compare supplement options. Always check the full ingredient list, directions for use and any allergen information on the product packaging before taking any food supplement.

Ingredients and important information

Ingredient lists and formulations may vary by batch or supplier. Always check the product packaging for the most up-to-date information. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily intake. If you are pregnant, nursing, taking medication or have a medical condition, consult your healthcare professional before use.

View full details
  • Tracked worldwide delivery

    Clear delivery messaging for shoppers worldwide.

  • Secure checkout

    Secure checkout.

  • Clear returns

    Returns information is written plainly before purchase.

  • Trusted brands

    Carefully selected supplements from established wellness brands.

Supplement guide

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings at UK Vitality Vitamins

Key Ingredients: SAM-e and TMGSAM-e (400 mg): S-Adenosylmethionine is a naturally occurring compound that acts as a methyl donor in over 100 biochemical reactions, including DNA methylation, protein modification, and ...

Category Blended Vitamin & Mineral Supplements
Delivery area Worldwide
Checkout Secure checkout
Brand XYMOGEN
Price £124.60
Availability In stock
allergen-freebetainecellular healthdetoxificationfood supplementgluten-freehomocysteineliver supportmethylation supportmood support

How to choose if this supplement fits your routine

Read the ingredient list, check the serving size and directions for use. Consider the supplement form (tablet, capsule, liquid) and whether it suits your dietary requirements. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

What UK Vitality Vitamins shows before checkout

Every product page displays price, availability, variant choices, ingredient information, directions for use, allergen details, worldwide delivery expectations and secure checkout — so you can make an informed decision quickly.

Questions about XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings

Is XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-free, Vegan - Lemon - 30 Servings available with worldwide delivery?

Yes. This product is currently available on UK Vitality Vitamins with free worldwide delivery.

How should I compare this with similar supplements?

Compare the active ingredients, serving size, number of servings per container, supplement form, brand reputation and price per serving. Check allergen information if relevant to your dietary needs.

Where can I find delivery and returns information?

Delivery information is shown near the add to basket area. Returns guidance is available on the product page and full terms are covered in the store returns policy.

Supplement shopping with clarity

UK Vitality Vitamins product pages display ingredients, directions, allergen details and delivery information clearly — so you can compare supplements and make informed choices quickly.